British quantity 4 Watson loved a memorable run to the final 16, her finest exhibiting in any grand slam.
However a quarter-final spot proved past the 30-year-old from Guernsey as German teen Niemeier gained 6-2 6-4.
Heather Watson’s Wimbledon run was ended within the fourth spherical by Centre Courtroom debutant Jule Niemeier.
Beforehand the gang had been handled to a parade of former champions together with Rod Laver, Billie Jean King, Bjorn Borg, Andy Murray and Roger Federer to have fun Centre Courtroom’s centenary.
Sadly, they then obtained to witness what has been a well-known sight over the past 100 years, that of a British participant being knocked out.
Niemeier, 22, could also be unseeded however she beat quantity two seed Anett Kontaveit within the second spherical, and illustrated her high quality with a surprising winner from the baseline as she chased down a Watson lob.
It was a flat first set from Watson, who was damaged twice and swatted the web in frustration after lacking a easy volley to carry up set level.
Residence hopes had been briefly raised when Watson confidently broke for a 2-0 lead within the second, however she was unable to again it up and double-faulted as Niemeier hit straight again.
Two extra double faults in her subsequent service sport spelled the top for Watson as Niemeier wrapped up victory in an hour and 17 minutes.